CMV Accelerates Epigenetic Aging

Cytomegalovirus infection accelerates epigenetic aging.

L Kananen, T Nevalainen, J Jylhävä, S Marttila, A Hervonen, M Jylhä, M Hurme. Exp Gerontol 2015 Oct 17 [Epub ahead of print].

Abstract
Epigenetic mechanisms such as DNA methylation (DNAm) have a central role in the regulation of gene expression and thereby in cellular differentiation and tissue homeostasis. It has recently been shown that aging is associated with profound changes in DNAm. Several of these methylation changes take place in a clock-like fashion, i.e. correlating with the calendar age of an individual. Thus, the epigenetic clock based on these kind of DNAm changes could provide a new biomarker for human aging process, i.e. being able to separate the calendar and biological age. Information about the correlation of the time indicated by this clock to the various aspects of immunosenescence is still missing. As chronic cytomegalovirus (CMV) infection is probably one of the major driving forces of immunosenescence, we now have analyzed the correlation of CMV seropositivity with the epigenetic age in the Vitality 90 + cohort 1920 (122 nonagenarians and 21 young controls, CMV seropositivity rates 95% and 57%, respectively). The data showed that CMV seropositivity was associated with a higher epigenetic age in both of these age groups (median 26.5 vs. 24.0 (p < 0.02, Mann–Whitney U -test) in the young controls and 76.0 vs. 70.0 (p < 0.01) in the nonagenarians). Thus, these data provide a new aspect to the CMV associated pathological processes.

http://www.sciencedirect.com/science/article/pii/S0531556515300711

More about CMV and Aging

Meanwhile, AS USUAL, the anti-smokers are committing scientific fraud by ignoring the role of CMV infection in order to exploit the circumstance that smokers are more likely to have been infected by it, beginning in childhood.

Depraved Senators’ Tantrum Over US Chamber of Commerce

(Washington, DC) – Today, U.S. Senators Richard Blumenthal (D-Conn.) and Dick Durbin (D-Ill.) led a letter with their colleagues Senators Sherrod Brown (D-Ohio), Jack Reed (D-R.I), Sheldon Whitehouse (D-R.I.), Al Franken (D-Minn.), Elizabeth Warren (D-Mass.), and Jeff Merkley (D-Ore.) to reconsider and refocus its efforts away from undermining global anti-smoking measures. Following reports of the Chamber’s lobbying to defeat anti-smoking regulations across the globe, the Senators wrote to Chamber President Tom Donahue citing the severe risk their efforts pose to worldwide public health and condemned the Chamber for using its name and power to stymie countries’ efforts to enforce life-saving tobacco restrictions. (Blumenthal, Durbin, Senate Colleagues, Urge US Chamber to Cease Efforts to Undermine Anti-Smoking Public-Health Measures. Wednesday, July 8, 2015.)

http://www.blumenthal.senate.gov/newsroom/press/release/blumenthal-durbin-senate-colleagues-urge-us-chamber-to-cease-efforts-to-undermine-anti-smoking-public-health-measures

Media Scum Gloat Over New Orleans Smoking Ban

New Orleans Bars Issue Last Call for Smoking

Remember the truth about how they got their beloved “EPA” report on secondhand smoke. It wasn’t even written by real EPA scientists, because they were against calling secondhand smoke a human carcinogen, and said so in their reviews. Instead, it was written by handpicked anti-smokers of the most militant ilk, who used illegal pass-through contracts to conceal their role. And on the board of directors of the crooked company that handled the pass-throughs sat Fred Malek, who was both a director of anti-smoker Sen. Frank Lautenberg’s company, ADP, and the campaign manager for President George Herbert Walker Bush, by whose administration the fraudulent report was released. And the mass media have deliberately concealed the truth all these years so they can FORCE their political agenda on the American people. And THAT is how their fraudulent so-called science and equally fraudulent so-called democracy really operate!

UK Government Tries to Incite Violence Against Smokers

“The public are encouraged to face punch #smokers if they dare light up in #Bristol” – TobaccoTactics UK

.@Dick_Puddlecote The public are encouraged to face punch #smokers if they dare light up in #Bristol. @soozaphone http://t.co/1sju1s8unb—
TobaccoTactics UK (@TobaccoTacticss) February 10, 2015

The UK’s National Health Service has resorted to the Nazi tactic of the pogrom to intimidate smokers! And the US government is sure to copy them if they get away with it!

Update: TobaccoTactics is run by the University of Bath’s Tobacco Control Research Group in its School of Public Health, among whom is Anna B. Gilmore, MBBS MSc PhD FFPH. Gilmore et al. have published a raft of tobacco control studies, including, “Support for a tobacco endgame strategy in 18 European countries.” It hardly needs to be said that “endgame” is the code word for outlawing tobacco.

http://www.ncbi.nlm.nih.gov/pubmed/25117519

Anna B. Gilmore at the University of Bath has received $1,290,944 from the US National Cancer Institute between 2011 and 2013, for the project “Tobacco Companies, Global Governance and Public Health.”

http://projectreporter.nih.gov/Reporter_Viewsh.cfm?sl=13EACD0C4784C1DE7598B8961CAA4A01A2FFCEB861BF

In 2014, she received a grant of £354,246 for “Understanding the impact of tobacco tax increases and tobacco industry pricing on smoking behaviours and inequalities,” from the UK National Institute for Health Research.

http://www.timeshighereducation.co.uk/news/grant-winners-27-november-2014/2017151.article

Why We Fight

Mass Censorship in New Orleans!

Lies, fraud, and conspiracy triumph again and again – all thanks to the Corporate Media! They use their First Amendment to rob the people of our liberties. We should take it away from them, and flush it down the toilet! Their biggest and most psychopathic lie is that smoking bans are about “freedom versus public health.” LIARS – they’re about fraud, fraud, fraud, fraud, and FRAUD! The deliberate use of scientific fraud by the government, against the people, to further the ends of TYRANTS.